Dr. Macdonald is Professor of Surgery, University of Toronto and attending neurosurgeon at St. Michael’s Hospital. He conducts clinical and translational research on the pathophysiology and treatment of subarachnoid hemorrhage, chronic subdural hematoma and vascular instability in cavernous malformations and brain microbleeding. He has written about 250 peer-reviewed publications, 2 books, and about 400 reviews, editorials and other published papers. He started a company, Edge Therapeutics, in 2008 in order to translate his laboratory work to the clinic. He is the chief scientific officer of Edge Therapeutics.